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Los riesgos son: aumento en la mortalidad fetal y neonatal y síndrome de aspiración de meconio, así como mayores cuidados neonatales.

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Hoofnagle JH; Drug-Induced Liver Injury Network. The mechanism of the interaction between propranolol and lidocaine is thought to be due to propranolol-induced decreased hepatic blood flow causing decreased elimination of lidocaine.

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Furthermore, allopurinol qualitest copper salts, such as CuCN or Cul may also be added to further enhance the reaction.